Endotoxins are biological molecules released from the outer membrane of certain bacteria. They may remain in water even after bacteria are reduced or killed. Pyrogens are substances that can cause fever or biological reactions, and endotoxins are one of the most important types of pyrogens in laboratory water applications.
Endotoxins are not living organisms. Therefore, technologies that kill bacteria do not necessarily remove endotoxins.
Endotoxins may come from:
If microbial growth is not controlled, endotoxin levels may increase over time.
Endotoxins can interfere with biological and clinical applications. They are especially important where water comes into contact with cells, biological reagents or sensitive clinical workflows.
Endotoxin contamination can cause:
Because endotoxins are not necessarily removed by standard ion exchange or UV disinfection, specific barriers may be required.
Endotoxins are controlled using:
For endotoxin-sensitive applications, ultrafiltration near the point of use is often important.
Endotoxins and pyrogens may affect:
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TKA Ultrapure Water Technologies India Pvt. Ltd. is an Indian company focused on the design, manufacture and support of laboratory water purification systems… Read More
